Jie Yang, Ph.D.

Assistant Professor, Department of Biochemistry and Molecular Genetics, School of Medicine

Yang Lab Receives UVA Cancer Center Pilot Awards

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The Yang Lab recently received the UVA Cancer Center Collaborative Pilot Single-Component Award with Dr. Shangming Tang and the Neuro TRT Pilot Award with Dr. Hui Li. We are grateful for the continued support from the UVA Cancer Center and are excited to advance these projects.

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Cryo-EM structures of human ClpXP reveal mechanisms of assembly and proteolytic activation

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Wenqian Chen, Gabriel C. Lander*, Jie Yang*

De novo design of protein binders that target DELE1 to inhibit the mitochondrial stress response

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Rui Yang*, Kaiyuan Zheng*, McGuire Metts, Yiluo Wang, Danyan Yin, Kevin P. Li, Agnieszka A. Prazmowska, David F. Kashatus, Brian Kuhlman, Jie Yang

Provisional patent filed for de novo designed DELE1 binders

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The Yang Lab has filed a provisional patent application through UVA Licensing and Ventures Group for engineered DELE1 binders that target the mitochondrial s...

Yang Lab has received pilot awards from the UVA Comprehensive Cancer Center

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We received the following pilot awards from the UVA Comprehensive Cancer Center in 2025: ACS-IRG Pilot Award, Cancer Biology Pilot Award, and Pediatric Pilot...

Jie Yang, Ph.D.

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Cryo-EM structures of human ClpXP reveal mechanisms of assembly and proteolytic activation

De novo design of protein binders that target DELE1 to inhibit the mitochondrial stress response

Provisional patent filed for de novo designed DELE1 binders

Yang Lab has received pilot awards from the UVA Comprehensive Cancer Center