Jie Yang, Ph.D.

Assistant Professor, Department of Biochemistry and Molecular Genetics, School of Medicine

The Yang Lab Receives the ACS-IRG Pilot Grant! (2025–2026)

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We are thrilled to receive the 2025–2026 American Cancer Society Institutional Research Grant (ACS-IRG) to support our pilot project focused on targeting mitochondrial stress signaling pathways in cancer.

We thank the UVA Cancer Center and the ACS for supporting our research!

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Cryo-EM structures of human ClpXP reveal mechanisms of assembly and proteolytic activation

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We recently published “Cryo-EM structures of human ClpXP reveal mechanisms of assembly and proteolytic activation” in bioRxiv.

The Yang Lab is hiring across all levels!

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We have open positions for Postdoctoral scholars, PhD students, and Research technicians. Please check the “Join” section for more information.

Jie is featured by the Thermo Fisher Cryo-EM webinar series

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Jie talked about the imapct of Cryo-EM in gaining mechanistic insights into protein targets that are important in health and disease.

DELE1 oligomerization promotes integrated stress response activation

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We recently published “DELE1 oligomerization promotes integrated stress response activation” in Nature structural & molecular biology.

Jie Yang, Ph.D.

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Cryo-EM structures of human ClpXP reveal mechanisms of assembly and proteolytic activation

The Yang Lab is hiring across all levels!

Jie is featured by the Thermo Fisher Cryo-EM webinar series

DELE1 oligomerization promotes integrated stress response activation