Jie Yang, Ph.D.
Assistant Professor, Department of Biochemistry and Molecular Genetics, School of Medicine
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Cryo-EM structures of human ClpXP reveal mechanisms of assembly and proteolytic activation
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Wenqian Chen, Gabriel C. Lander*, Jie Yang*
De novo design of protein binders that target DELE1 to inhibit the mitochondrial stress response
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Rui Yang*, Kaiyuan Zheng*, McGuire Metts, Yiluo Wang, Danyan Yin, Kevin P. Li, Agnieszka A. Prazmowska, David F. Kashatus, Brian Kuhlman, Jie Yang
Provisional Patent Filed for De Novo–Designed DELE1 Binders
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A provisional patent application has been filed through UVA Licensing & Ventures Group for the Yang Lab’s engineered DELE1 binders targeting the mitochon...
The Yang Lab has received pilot awards from the UVA Comprehensive Cancer Center
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We received the following pilot awards from the UVA Comprehensive Cancer Center in 2025: ACS-IRG Pilot Award, Cancer Biology Pilot Award, and Pediatric Pilot...